0M0A0298.JPG

Mr Matthew Read

FRACS, MBBS, PhD
Oesophago-Gastric, Bariatric Surgeon and General Surgeon

Mr Matthew Read is a general and upper gastrointestinal surgeon with a special interest in minimally invasive surgery. After completing his general surgical fellowship in 2016, Matthew was accepted by the Australian and New Zealand Gastro-Oesophageal Surgery Association (ANZGOSA) for subspecialty training in the field of upper gastrointestinal surgery. This was undertaken at both St Vincent's and The Alfred Hospitals in Melbourne. Following this, Matthew undertook a surgical oncology fellowship with a special focus on robotic surgery at the University Medical Center in Utrecht, the Netherlands, under the supervision of Prof Richard van Hillegersberg.

Matthew has also recently completed a PhD through the University of Melbourne and the Peter MacCallum Cancer Centre, which was focused on the development of preclinical models to better understand oesophageal cancer and its precursor, Barrett’s oesophagus. This work has led to numerous publications, awards and international collaborations. Most recently, Matthew was awarded the senior lecturer fellowship from the Royal Australasian College of Surgeons and was appointed to the advisory board of OESO, a worldwide organisation which focuses on diseases of the oesophagus. Matthew has also been elected to a position on the Academia surgical Committee as the Younger Fellow Representative.

 Education and Experience

  • Upper GI Fellow (ANZGOSA), the Alfred Hospital, 2018

  • Upper GI Fellow (ANZGOSA), St Vincent’s Hospital, Melbourne, 2017

  • Fellowship of the Royal Australasian College of Surgeons (RACS), General Surgery, 2016

  • Bachelor of Medicine and Bachelor of Surgery, Monash University, 2003

 

Current Research Interests

  • Basic biology of Barrett’s oesophagus and oesophageal adenocarcinoma

  • Development of novel treatments for Barrett’s oesophagus and oesophageal adenocarcinoma

  • Development of clinical guidelines for upper gastrointestinal conditions (OESO)

  • Developing a robotic upper gastrointestinal surgical program

  • Outcomes following fundoplication in lung transplant recipients

 

Publications

  • Read MD, Krishnadath KK, Clemons NJ, Phillips WA. Preclinical models for the study of Barrett’s carcinogenesis. Ann N Y Acad Sci. 2018 Jul 5. doi: 10.1111/nyas.13916.

  • David S. Liu, Cuong P. Duong, Sue Haupt, Karen G. Montgomery, Colin M. House, Walid J. Azar, Helen B. Pearson, Oliver M. Fisher, Matthew Read, Glen R. Guerra, Ygal Haupt, Carleen Cullinane, Klas G. Wiman, Lars Abrahmsen, Wayne A. Phillips & Nicholas J. Clemons. Inhibiting the system xC/glutathione axis selectively targets cancers with mutant-p53 accumulation. Nature Communications 2017. DOI: 10.1038/NCOMMS14844.

  • Liu DS, Hoefnagel SJ, Fisher OM, Krishnadath KK, Montgomery KG, Busuttil RA, Colebatch AJ, Read M, Duong CP, Phillips WA, Clemons NJ. Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis. Oncotarget. 2016 Dec 13;7(50).

  • Liu DS, Read M, Cullinane C, et al. APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma. Gut 2015. DOI: 10.1136/gutjnl-2015-309770.

  • Read M, Liu D, Duong CP, Cullinane C, Murray W, Fennell C, Shortt J, Westerman D, Burton P, Clemons NJ, Phillips WA. Intra-muscular transplantation improves engraftment rates for esophageal patient-derived tumor xenografts. Annal of Surg Onc. DOI: 10.1245/s10434-015-4425-3.

 

Local Presentations

  • M Read. Barrett’s Oesophagus. ANZGOSA Training Day, Melbourne, 2019.

  • M Read. Surgical Academia. SUGGS Meeting, Sydney, 2017.

  • M Read, A Correia, D Liu, D Straub, N Clemons, C Duong, K.K. Krishnadath & W Phillips. Reversing Barrett’s Metaplasia in a Novel Organoid Model. Combined ANZGOSA / SUGGS Meeting, Sydney, 2016.

  • M Read, S Calpe, D Liu, D Straub, N Clemons, C Duong, K.K. Krishnadath & W Phillips. Targeting the BMP pathway in Barrett’s carcinogenesis for molecular imaging & therapeutics. General Surgeons Australia, Annual Scientific Meeting, Cairns, 2015.

  • Matthew Read, David Liu, Nicholas Clemons, Christina Fennell, Cuong Duong & Wayne Phillips. A novel xenograft model for investigating Barrett’s carcinogenesis. Australian Health and Medical Research Congress, Melbourne, Australia. 2014.

  • Matthew Read, Nicholas Clemons, Christina Fennell, Cuong Duong & Wayne Phillips. Patient derived tumour xenografts and the development of personalized medicine in oesophageal adenocarcinoma. Combined IsDEAS & ANZGOSA Meeting, Melbourne. 2013.

 

International Presentations

  • M Read. Oesophageal Cancer. ANZGOSA Meeting, Wellington, 2018.

  • M. Read. Esophageal Stem Cells (Invited Talk). OESO, Geneva, 2017.

  • M. Read, A. Correia, S. Calpe, N. Clemons, D. Liu, W.A. Phillips, K.K. Krishnadath. Remodeling Barrett’s Metaplasia in a Novel In Vivo Organoid Model. Digestive Diseases Week, Chicago, 2017.

  • M. Read, Krishnadath KK, Liu DSH, Duong CP, Clemons NJ, Phillips WA*. A novel xenograft model of human Barrett’s esophagus. Digestive Diseases Week, San Diego, 2016.

  • Phillips WA, Read M, Liu D, Fennel C, Duong C, Clemons N. Patient Derived Tumor Xenografts: Preclinical Models for Personalising Therapy for Esophageal Cancers. 14th World Congress of the International Society for Diseases of the Esophagus, Vancouver, Canada. Abstract published in Diseases of the Esophagus. 2014; 27 (Supp): 64A.

  • M Read, D Liu, MP Bernardi, C Duong, N Clemons, W Phillips. A novel pre-clinical model for the study of Barrett’s oesophagus. Annual Scientific Congress of the Royal Australasian College of Surgeons, Singapore. 2014. Abstract published in ANZ Journal of Surgery. 2014; 84: 209.

  • Matthew Read, Nicholas Clemons, Wayne Phillips, Christina Fennell & Cuong Duong. An improved xenograft model for testing novel therapies in oesophageal adenocarcinoma. Annual Scientific Congress of the Royal Australasian College of Surgeons, Auckland. 2013. Abstract published in ANZ J. Surg. 2013; 83 (Suppl. 1) 98-104.

  • Read, M., Croagh, D., Clemons, N. J., Fennell, C., Duong, C., Phillips, W. A. Developing a novel in vivo tissue reconstitution system for the study of Barrett’s oesophagus. 13th World Congress of the International Society for Diseases of the Esophagus, Venice, Italy (oral presentation). Abstract published in Diseases of the Esophagus. 2012; 25 (Supp.1): 57A.

 

Awards

2018

  • ANZGOSA Travelling Scholarship

2017

  • Peter Ryan Prize (Best Surgical Research Paper)
    St Vincent’s Hospital Research Week

  • ANZGOSA Travelling Scholarship

2016

SUGGS Medtronic Travelling Scholarship – Awarded for Best Oral Presentation. Combined ANZGOSA/SUGSS Meeting, Sydney

2015

  • Best Early Career Investigator – Oral Presentation
    Cabrini Research Day

2015

  • John Ham Medal.
    GSA Annual Scientific Meeting, Cairns

2014

  • Best Trainee Presentation, Upper GI Surgery Section.
    Annual Scientific Congress, Singapore

2013

  • Professor Robert Thomas Translational Research Award.
    The Peter MacCallum Cancer Centre

2013

  • Best Trainee Presentation, Surgical Oncology Section.
    Annual Scientific Congress, Auckland

 

Scholarships

2019

  • Inaugural Surgeons’ Impact Fund Research Scholar, St Vincent’s Hospital, Melbourne

2015

  • Viola Edith Reid Bequest, Faculty of Medicine, The University of Melbourne

2012 & 2014

  • Sir Thomas Naghten Fitzgerald Scholarship, Faculty of Medicine, The University of Melbourne

2013

  • Francis and Phyllis Thornell Shore Memorial Scholarship - Royal Australasian College of Surgeons

 

Teaching Roles

  • Clinical Tutor, The University of Melbourne (2018 to present)

  • ASSET instructor, RACS (2017 to present)

 

Public Hospital Appointments

  • Upper Gastrointestinal Surgeon, St Vincent’s Health, Melbourne

  • Upper Gastrointestinal Surgeon, Royal Melbourne Hospital

 

Professional Associations

  • FRACS – Fellow of the Royal Australian College of Surgeons

  • ANZGOSA – Australia and New Zealand Gastro-Oesophageal Surgery Association

  • ANZHPBA – Australia and New Zealand Hepato-Pancreato-Biliary Association

  • OESO – Member of the Permanent Scientific Committee

 

RACS Involvement

(Royal Australasian College of Surgeons)

  • Local Coordinator of the General Surgery Fellowship Exam (2017 & 2019)

  • Faculty member of the Australian & New Zealand Surgical Skills Education and Training Course (ASSET) (2017 to present)

  • Co-coordinator of the Annual Scientific Conference - Bariatric & Upper Gastrointestinal Surgery sections (2020)

 

Qualifications

  • FRACS, MBBS, PhD

  • Oesophago-Gastric, Bariatric and General Surgeon