Water-Soluble Vitamin Deficiencies Following Laparoscopic Single-Anastomosis Gastric Bypass


Water-soluble vitamins include the B-complex group – thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folate (B9) and cobalamin (B12) – as well as vitamin C. These vitamins cannot be made by the body and must be regularly ingested in small quantities to prevent disorders of metabolism.

After food consumption, water-soluble vitamins are absorbed in the small bowel and utilized in several body processes. The body’s limited capacity to store water-soluble vitamins leaves patients particularly prone to the consequences of vitamin deficiencies following weight loss procedures. So far, no studies have identified the impact of a single-anastomotic gastric bypass on water-soluble vitamin levels.


Aim:

  • To determine the prevalence of pre surgery water soluble vitamin deficiencies in bariatric (weight loss) surgery candidates (BMI ≥ 40 kg/m2 or BMI ≥ 35kg/m2 with obesity-related comorbidities)
  • To determine the incidence of long term water-soluble vitamin deficiency in participants who have had single-anastomosis gastric bypass
  • To evaluate the effectiveness of current nutritional and supplement strategies in recruited participants
 
 

Status: Currently recruiting

Site: St Vincent’s Hospital Melbourne

Ethics: HREC/16/SVHM/219

Principal Investigator: Mr Simon Banting

 

Eligibility

Inclusion

  • Adults 18 years of age with a BMI>40 kg/m2 or BMI>35 kg/m2 with obesity-related comorbidities

  • Undergoing elective single-anastomosis gastric bypass for weight loss surgery

Exclusion

  • Non English speaking

  • Unable to provide own consent

Outcome Measures

  • B-complex vitamin group levels

  • Vitamin C levels

  • Adherence to vitamin supplementation